Description

Duratia 60 – Dapoxetine 60 mg Tablets for Premature Ejaculation

Manufacturer: Fortune Health Care
Active Substance: Dapoxetine (60 mg per tablet)
Pack Size: 10 tablets x 60 mg

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Product Description

Duratia 60 is a pharmaceutical preparation containing dapoxetine hydrochloride, a selective serotonin reuptake inhibitor (SSRI) specifically developed for the on-demand treatment of premature ejaculation in adult men. Each film-coated tablet delivers 60 mg of dapoxetine, the maximum recommended single dose for this indication.

Premature ejaculation is a prevalent male sexual dysfunction affecting an estimated 20–30% of men globally. Dapoxetine is proposed to delay ejaculation through potentiation of the actions of serotonin. By inhibiting the serotonin transporter, concentrations of the neurotransmitter in the synapse and the extracellular space around neuronal cell bodies are increased. Recent research has identified a novel mechanism wherein dapoxetine upregulates the dopamine D4 receptor, which enhances its therapeutic effect in premature ejaculation treatment.

Clinical studies demonstrate that dapoxetine 60 mg significantly improves intravaginal ejaculatory latency time (IELT). In a 24-week study involving 1,162 European males with premature ejaculation, the 60 mg dose produced a mean IELT of 3.5 minutes at Week 24 compared to 0.88 minutes at baseline. The responder rate—defined as the proportion of subjects achieving a ≥2 category increase in control over ejaculation and ≥1 category decrease in personal distress—was 37% for the 60 mg dose, compared to 13% for placebo. In a separate 12-week study of 1,067 Asian/Pacific males, the 60 mg dose achieved a responder rate of 37% versus 22% for placebo. Improvement was observed from the first dose.

Dapoxetine is rapidly absorbed, with maximum plasma concentration reached approximately 1–2 hours after tablet intake, and it has rapid elimination as evidenced by low concentration 24 hours after dosing. The recommended dosing schedule is one tablet taken 1 to 3 hours prior to anticipated sexual activity, not to exceed one tablet within any 24-hour period. Treatment should not be initiated with the 60 mg dose; patients are typically started on 30 mg and may be increased to 60 mg if the lower dose is well tolerated.

Duratia 60 is manufactured by Fortune Health Care, a pharmaceutical company committed to quality and consistency in production. Each tablet is formulated to ensure reliable bioavailability and predictable pharmacokinetic performance.

Systematic reviews and meta-analyses indicate that while dapoxetine is recognized for its beneficial effects, its clinical efficacy is significantly enhanced when combined with non-pharmacological interventions such as behavioral therapy, pelvic floor muscle training, and psychoeducation. Combination therapy increases IELT, reduces Premature Ejaculation Diagnostic Tool (PEDT) scores, and improves Premature Ejaculation Profile (PEP) scores compared to dapoxetine monotherapy.

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Top 10 Frequently Asked Questions

1. What is Duratia 60 and what is it used for?

Duratia 60 is a medication containing dapoxetine 60 mg, a selective serotonin reuptake inhibitor (SSRI) used for the treatment of premature ejaculation in adult men. It is taken on demand, approximately 1 to 3 hours before sexual activity, to increase the time to ejaculation and improve control over ejaculation.

2. How should I take Duratia 60?

Take one tablet with a full glass of water 1 to 3 hours before anticipated sexual activity. Do not take more than one tablet in any 24-hour period. The recommended starting dose is 30 mg; the 60 mg dose should only be taken if the 30 mg dose has been previously used and is well tolerated. Duratia is not intended for continuous daily use.

3. What are the common side effects of Duratia 60?

The most common side effects include dizziness, nausea, and headache. In clinical trials, nausea was the most frequently reported adverse event, occurring in 30.6% of patients taking the 60 mg dose. Dizziness, disturbance in attention, syncope (fainting), blurred vision, and somnolence have also been reported. Drinking a full glass of water with the tablet can help reduce nausea and dizziness.

4. Are there any contraindications for using Duratia 60?

Duratia 60 should not be used in combination with other SSRIs, monoamine oxidase inhibitors (MAOIs), or other serotonergic medicinal or herbal products, nor within 14 days of discontinuing such treatments. It should be used with caution in patients with a tendency to faint, heart conditions, bleeding or clotting disorders, epilepsy, bipolar disorder, depression, mania, glaucoma, or liver and kidney impairment. Patients should avoid alcohol and grapefruit juice while taking this medication.

5. Is dapoxetine FDA approved?

Dapoxetine is not currently approved by the U.S. Food and Drug Administration (FDA) for the treatment of premature ejaculation. The manufacturer received a Non-Approvable letter from the FDA in 2005. However, dapoxetine has received regulatory approval in numerous other countries worldwide, including Australia and countries within the European Union and Asia. It is the first medication to be officially approved for this indication in many jurisdictions.

6. How effective is dapoxetine 60 mg?

Clinical trials demonstrate significant efficacy. In a 24-week study, the 60 mg dose produced a mean IELT of 3.5 minutes compared to 0.88 minutes at baseline, with a responder rate of 37% versus 13% for placebo. A separate 12-week study showed a responder rate of 37% for the 60 mg dose compared to 22% for placebo. Dapoxetine has been shown to increase IELT by 2.5 to 3.0-fold.

7. What should I do if Duratia 60 does not seem effective?

If Duratia 60 does not provide the expected results, consult your healthcare provider to discuss effectiveness. Consideration should be given to whether the tablet was taken at the correct time (1 to 3 hours before sexual activity) and with a full glass of water. Your doctor may evaluate whether a different dose or an alternative treatment approach is more appropriate. Clinical evidence suggests that combining dapoxetine with non-pharmacological therapies such as behavioral therapy or pelvic floor muscle training can significantly enhance outcomes.

8. Can I take Duratia 60 with other medications?

Duratia 60 has significant drug interactions. It must not be taken with other SSRIs, MAOIs, or serotonergic agents. Caution is required when used with medications that affect serotonin levels, as this increases the risk of serotonin syndrome. The efficacy and safety of dapoxetine in combination with PDE5 inhibitors (used for erectile dysfunction) have not been established. Always inform your healthcare provider about all medications, including over-the-counter products and herbal supplements, before taking Duratia 60.

9. Can I drink alcohol while taking Duratia 60?

No. Alcohol consumption should be avoided while taking Duratia 60. Combining dapoxetine with alcohol may increase alcohol-related neurocognitive effects and may potentiate neurocardiogenic adverse drug reactions such as syncope (fainting), thereby increasing the risk of accidental injury.

10. Where can I buy Duratia 60?

Duratia 60 is available for purchase through authorized online pharmacies. To ensure you receive genuine product, purchase only from trusted sources. Duratia 60 can be ordered at: https://anabolicsteroidsonline.shop/. Always consult a healthcare professional before starting any new medication.

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Important Safety Information

• This medication is for adult men only.

• Do not exceed the recommended dose of one tablet per 24 hours.

• Do not take this medication if you are allergic to dapoxetine or any of the tablet excipients.

• Patients should be warned to avoid situations where injury could result from dizziness or fainting, including driving or operating hazardous machinery.

• Seek immediate medical attention if you experience swollen face, eyes, lips, or tongue; difficulty breathing; or itchy skin rashes.

• This product is not a substitute for professional medical advice. Always consult a qualified healthcare provider regarding your specific health condition.

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References

1. Drugs.com. Priligy (dapoxetine) FDA Approval Status. https://www.drugs.com/history/priligy.html 

2. Therapeutic Goods Administration (Australia). AusPAR Priligy Dapoxetine. https://www.tga.gov.au/ 

3. Patient.info. Dapoxetine tablets. https://patient.info/ 

4. PubMed / National Library of Medicine. Dapoxetine combined with non-pharmacological approaches for lifelong premature ejaculation: A systematic review and meta-analysis. https://pubmed.ncbi.nlm.nih.gov/41020367/ 

5. PubMed / National Library of Medicine. Vital function of DRD4 in dapoxetine medicated premature ejaculation treatment. https://pubmed.ncbi.nlm.nih.gov/36746766/ 

6. PMC / National Library of Medicine. Comparative evaluation of safety and efficacy of dapoxetine, silodosin, and citalopram in the management of premature ejaculation: a randomized clinical trial. https://pmc.ncbi.nlm.nih.gov/articles/PMC12667069/