Description

Buy XT Labs Oxandroplex 10

Oxandrolone 10mg – 60 Tablets

Product Description

Oxandrolone, commonly known by the brand names Anavar and Oxandrin, is a synthetic anabolic-androgenic steroid (AAS) that has been utilized in medical settings since its introduction in 1964. This oral tablet contains 10 mg of oxandrolone per tablet, with a total supply of 60 tablets per bottle—a dosage strength and quantity consistent with previously available pharmaceutical preparations.

Mechanism of Action

Oxandrolone acts as an agonist of the androgen receptor (AR), the biological target of androgens such as testosterone and dihydrotestosterone. It exhibits both anabolic (muscle-building) and androgenic (hormone-related) effects. The compound binds to androgen receptors in muscle and other tissues, increasing protein synthesis and nitrogen retention. Unlike many other anabolic steroids, oxandrolone does not aromatize (convert to estrogen), which means it does not carry the same risk of estrogen-related side effects such as gynecomastia.

Pharmacokinetic Profile

Oral oxandrolone demonstrates high bioavailability, with an estimated bioavailability of approximately 97%. The mean elimination half-life is approximately 9 to 10 hours in younger individuals and approximately 13.3 hours in elderly subjects. Metabolism occurs primarily in the liver, with excretion occurring via urine (approximately 90%) and feces (approximately 6%).

Medical Indications

Oxandrolone has been indicated as adjunctive therapy for several medical conditions, including:

• Promotion of weight gain following weight loss after extensive surgery, chronic infections, or severe trauma

• Offset of protein catabolism associated with prolonged administration of corticosteroids

• Relief of bone pain frequently accompanying osteoporosis

• Support for patients who fail to gain or maintain normal weight without definite pathophysiologic reasons

Clinical research has also explored oxandrolone’s efficacy in wound healing, with studies examining its potential benefits for burn patients and individuals with decubitus ulcers.

Regulatory Status

Oxandrolone is classified as a controlled substance under the Anabolic Steroids Control Act of 1990 and has been assigned to Schedule III (non-narcotic). The FDA-approved forms of oxandrolone (Oxandrin) have been discontinued and are no longer available in the United States.

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Top 10 Frequently Asked Questions

1. What is the recommended dosage of oxandrolone?

Medical dosing for oxandrolone typically ranges from 2.5 mg to 20 mg per day, administered in divided doses two to four times daily. Therapeutic courses generally last two to four weeks. Individual dosing should be based on the specific condition being treated and patient response. Higher doses are sometimes used in non-medical contexts, but such use carries significantly increased risks.

2. What are the most common side effects of oxandrolone?

Common side effects include nausea, vomiting, changes in skin color, fluid retention (swollen ankles), changes in genital size, erectile dysfunction, changes in sex drive, mood changes (including depression or restlessness), sleep disturbances, irregular menstrual periods, breast changes, excessive hair growth or hair loss, and acne.

3. Is oxandrolone safe for the liver?

Oxandrolone is a 17-alpha-alkylated oral steroid, which means it passes through the liver and carries a risk of hepatotoxicity. Serious liver conditions including peliosis hepatis (blood-filled cysts in the liver) and liver cell tumors have been reported in patients receiving anabolic steroid therapy. Liver injury can occur even with therapeutic use, and the drug was withdrawn from sale in the US in 2023 due to safety concerns.

4. Does oxandrolone affect natural testosterone production?

Yes. During exogenous administration of anabolic androgens, endogenous testosterone release is inhibited through suppression of pituitary luteinizing hormone (LH). At higher doses, spermatogenesis may also be suppressed through feedback inhibition of follicle-stimulating hormone (FSH).

5. What is the half-life of oxandrolone?

The elimination half-life of oral oxandrolone is approximately 9 to 10 hours in younger individuals. In elderly subjects, the mean elimination half-life has been reported as approximately 13.3 hours.

6. Are there any drug interactions with oxandrolone?

Oxandrolone has been reported to interact with several medications. Serious interactions include increased effects of cyclosporine (due to decreased metabolism), potential hepatotoxicity when combined with pexidartinib or pretomanid, and enhanced anticoagulant effects when taken with warfarin. Oxandrolone may also affect the metabolism of oral hypoglycemic agents.

7. Who should not take oxandrolone?

Oxandrolone is contraindicated in individuals with known or suspected carcinoma of the prostate or male breast, carcinoma of the breast in females with hypercalcemia, pregnancy (due to risk of fetal masculinization), nephrosis, and hypercalcemia.

8. Does oxandrolone cause hair loss?

The FDA drug label for oxandrolone lists androgenetic alopecia (pattern hair loss) as a potential side effect in women. Hair loss is a recognized side effect associated with anabolic steroid use and can occur in susceptible individuals.

9. Is oxandrolone legal to purchase without a prescription?

Oxandrolone is a Schedule III controlled substance in the United States and is available by prescription only. Non-medical possession or distribution is illegal. In Australia, oxandrolone is a Schedule 4 prescription-only medicine, and use without a prescription is illegal.

10. Does oxandrolone affect cholesterol levels?

Yes. Anabolic steroids, including oxandrolone, have been reported to increase low-density lipoproteins (LDL or “bad” cholesterol) and decrease high-density lipoproteins (HDL or “good” cholesterol). These levels typically revert to normal upon discontinuation of treatment. This effect can increase cardiovascular risk with prolonged use.

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References and Reputable Sources

• FDA Labeling Information: U.S. Food and Drug Administration

• DailyMed (NIH): Oxandrolone Tablets, USP CIII

• WebMD: Oxandrolone (Anavar, Oxandrin) – Uses, Side Effects, and More

• Medscape: Oxandrin (oxandrolone) dosing, indications, interactions

• PubMed Central (NIH): Oxandrolone efficacy in wound healing

• PubMed Central (NIH): Systematic review of oxandrolone in burn patients