Description

Mesterolone (Proviron) ZPHC — 25 mg (100 tablets)

Product Overview

Mesterolone 25mg by ZPHC is a potent oral androgen preparation designed for testosterone replacement therapy and the management of conditions associated with androgen deficiency. Each tablet contains 25 mg of the active ingredient, Mesterolone, in a convenient oral form. This product is manufactured by ZPHC, a quality pharmaceutical manufacturer, and comes in a pack of 100 tablets.

Mesterolone, commonly known by the brand name Proviron, is a synthetic derivative of dihydrotestosterone (DHT). It is indicated for the treatment of male hypogonadism, a condition where the body does not produce sufficient testosterone, and for male infertility related to low androgen levels . Official medical sources state that Proviron is used in men who do not naturally produce enough androgens and in men who are infertile due to low levels of male hormones caused by hypogonadism .

Mechanism of Action

Mesterolone acts as an androgen by binding to androgen receptors, promoting protein synthesis and nitrogen retention in muscles. It is known to have androgenic properties and can help increase free testosterone levels by binding to sex hormone-binding globulin (SHBG), thereby displacing endogenous testosterone and making it more bioavailable . This mechanism supports the development and maintenance of male secondary sexual characteristics, muscle mass, and strength .

Product Features

• Active Ingredient: Mesterolone

• Concentration: 25 mg per tablet

• Presentation: Pack of 100 oral tablets

• Manufacturer: ZPHC

• Form: Oral tablets

• Half-Life: Approximately 12-13 hours 

Indications and Benefits

Based on official product information, Mesterolone is indicated for:

• Androgen Deficiency: Treatment of conditions caused by deficient formation of endogenous androgens, which may manifest as decreased physical activity, rapid fatigability, decreased memory and concentration, libido and potency disturbances, irritability, and depressive mental states .

• Hypogonadism: Stimulates the growth, development, and function of androgen-dependent target organs and the development of secondary male sexual characteristics in cases of pre-pubertal androgen insufficiency .

• Male Infertility: Increases sperm count and improves sperm quality by raising and normalizing fructose concentration in the ejaculate, thereby increasing fertilization possibilities .

Dosage and Administration

Mesterolone tablets should be swallowed whole with some liquid. Dosage should be determined by a healthcare professional based on individual clinical needs. The following are general dosage guidelines from official sources:

• For Androgen Deficiency: One tablet (25 mg) three times daily to start. After satisfactory clinical improvement, a maintenance dose of one tablet once or twice daily may be sufficient .

• For Hypogonadism: For the stimulation of secondary male sexual characteristics, 1-2 tablets three times daily for several months. Maintenance: 1 tablet 2-3 times per day .

• For Infertility: 1 tablet 2-3 times per day for a complete spermatogenic cycle (approximately 90 days) .

Side Effects

Like all medicines, Mesterolone can cause side effects, although not everyone gets them. The following side effects have been reported with androgens in general and with Mesterolone specifically :

• Androgenic effects such as acne, alopecia (hair loss), and increased body hair

• Changes in libido

• Headache

• Frequent or prolonged erections, and priapism (painful, persistent erections)

• Abdominal pain

• Potential for liver toxicity (rare cases of benign and malignant liver tumors have been observed after use of hormonal substances like Proviron) 

• Changes in serum lipid profiles

• Fluid retention

• Mood changes, including aggression or depression 

Contraindications

Mesterolone should not be used by individuals with the following conditions :

• Prostate cancer

• Previous or existing liver tumors

• Male breast cancer

• Hypersensitivity to Mesterolone or any excipients

• It is contraindicated in women, particularly during pregnancy and breastfeeding 

Warnings and Precautions

• Medical Supervision: This product should be used under the supervision of a healthcare professional. Regular monitoring of prostate, liver function, and lipid profile is recommended .

• Abuse Warning: Official sources warn against the use of Proviron for bodybuilding or for increasing muscle mass in healthy men, as such use carries serious health risks, including cardiovascular events, liver damage, psychiatric events, and dependency .

• Prostate Examinations: Regular examinations of the prostate should be carried out as a precautionary measure, as androgens can accelerate the growth of subclinical prostate cancer or benign prostatic hyperplasia .

• Athletes: This medicine contains an active ingredient that can produce positive results in anti-doping tests .

Frequently Asked Questions (FAQs)

1. What is Mesterolone (Proviron) used for?
Mesterolone is used as testosterone replacement therapy in men with hypogonadism (a condition where the body does not produce enough testosterone) and for male infertility related to low androgen levels .

2. Is Mesterolone the same as testosterone?
No, Mesterolone is a synthetic derivative of dihydrotestosterone (DHT), a natural metabolite of testosterone. It has androgenic properties similar to testosterone but does not typically convert to estrogen .

3. What are the common side effects of taking Mesterolone?
Common side effects may include acne, hair loss, headache, frequent erections, and abdominal pain . More serious side effects, such as liver tumors or prostate issues, are rare but possible .

4. How is Mesterolone taken?
Mesterolone tablets are taken orally, swallowed whole with some liquid. The dosage and frequency are determined by a doctor but commonly range from 25 mg to 100 mg per day, divided into several doses .

5. Can Mesterolone be used for bodybuilding?
Official medical sources explicitly state that Proviron is not suitable for bodybuilding, increasing muscles in healthy men, or for increasing other physical abilities. Such use carries serious health risks .

6. Are there any interactions with other medications?
Yes, Mesterolone may interact with various medications, including oral anticoagulants (like warfarin), antidiabetic drugs, cyclosporine, and others. It is important to inform a healthcare provider of all medications being taken .

7. Can women take Mesterolone?
Mesterolone is for use in male patients only and is contraindicated in women, especially those who are pregnant or breastfeeding .

8. How long does Mesterolone stay in the body?
The plasma half-life of Mesterolone is approximately 12-13 hours . Detection times for athletes can be up to 5-6 weeks, depending on the test.

9. What happens if I miss a dose?
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one .

10. How should Mesterolone be stored?
Store Mesterolone in a cool, dry place, away from direct sunlight and out of the reach of children .

Disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Mesterolone is a prescription medication and should only be used under the supervision of a qualified healthcare provider. The use of androgens for non-medical purposes, such as performance enhancement, is discouraged due to serious health risks and is often prohibited in competitive sports . Always consult with a physician before starting any new medication or therapy.

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