Description

Vilitra 60 mg Tablets – Vardenafil 60 mg by Centurion Laboratories

Product Overview

Vilitra 60 is a pharmaceutical formulation containing vardenafil hydrochloride as its active substance, manufactured by Centurion Laboratories. Each tablet provides 60 mg of vardenafil, a potent and selective phosphodiesterase type 5 (PDE5) inhibitor indicated for the management of erectile dysfunction in men.

Vardenafil, the active ingredient in Vilitra 60, works by selectively inhibiting the PDE5 enzyme, which is responsible for the hydrolysis of cyclic guanosine monophosphate in the corpus cavernosum tissue of the penis. This inhibition results in increased arterial blood flow to the penile tissue, leading to enlargement of the corpus cavernosum and the subsequent achievement and maintenance of an erection during sexual stimulation. Vardenafil has high bioavailability and is rapidly absorbed following oral administration.

Clinical studies have demonstrated that vardenafil significantly improves erectile function across a range of patient populations. In a 26-week trial involving 736 men with erectile dysfunction of varied aetiologies, 85 percent of patients receiving vardenafil 20 mg reported improved erectile function compared with 28 percent of placebo recipients. Additionally, in a 12-week placebo-controlled trial, the rate of successful intercourse attempts was significantly higher with vardenafil at 71 to 75 percent compared with 39.5 percent in the placebo group.

Product Specifications

Mechanism of Action

Vardenafil exerts its therapeutic effect through selective inhibition of phosphodiesterase type 5, the predominant PDE enzyme responsible for the degradation of cyclic guanosine monophosphate in penile smooth muscle cells. By preventing the breakdown of cGMP, vardenafil promotes sustained smooth muscle relaxation in the corpus cavernosum, facilitating increased blood inflow and venous compression that together produce a rigid erection.

This mechanism is dependent on sexual stimulation, which triggers the release of nitric oxide and the subsequent activation of guanylate cyclase, leading to elevated cGMP levels. Vardenafil does not induce erections in the absence of sexual arousal and does not affect sexual desire.

Dosage and Administration

The recommended starting dose of vardenafil for most patients is 10 mg, taken orally as needed, approximately 60 minutes before sexual activity. The dose may be increased to a maximum recommended dose of 20 mg or decreased to 5 mg based on individual efficacy and tolerability.

Vilitra 60 provides a 60 mg strength, which represents a higher dosage option. Patients should consult with a qualified healthcare provider to determine the appropriate dosage for their specific condition and medical history. Vardenafil should not be taken more than once every 24 hours.

Side Effects and Precautions

Common adverse reactions reported in clinical trials with vardenafil include headache, flushing, nasal congestion, dyspepsia, dizziness, sinusitis, flu syndrome, increased creatine kinase, nausea, and back pain. These effects are typically mild to moderate in intensity and are often dose-dependent.

Vilitra 60 is contraindicated in patients taking nitrates or riociguat, as concomitant use can lead to severe hypotension. Patients with cardiovascular conditions, low blood pressure, liver or kidney impairment, or relevant ophthalmic history should exercise caution and seek medical advice before use.

Frequently Asked Questions

1. What is Vilitra 60 used for?

Vilitra 60 contains vardenafil and is used to treat erectile dysfunction, which is the inability to achieve or maintain an erection sufficient for satisfactory sexual performance.

2. How does Vilitra 60 work?

Vilitra 60 works by inhibiting the phosphodiesterase type 5 enzyme, which increases blood flow to the penis during sexual stimulation, facilitating the achievement and maintenance of an erection.

3. What is the recommended dosage of Vilitra 60?

The standard recommended starting dose for vardenafil is 10 mg, taken approximately 60 minutes before sexual activity. The maximum recommended dose is 20 mg. Vilitra 60 provides a 60 mg strength and should only be used under medical supervision.

4. How should Vilitra 60 be taken?

Vilitra 60 tablets should be taken orally with or without food, approximately 60 minutes before sexual activity. The tablet should not be taken more than once every 24 hours.

5. What are the common side effects of Vilitra 60?

Common side effects reported with vardenafil include headache, flushing, nasal congestion, indigestion, dizziness, and back pain.

6. Who should not take Vilitra 60?

Vilitra 60 should not be taken by individuals using nitrates or riociguat. Patients with severe cardiovascular conditions, recent heart attack or stroke, severe liver impairment, or hypersensitivity to vardenafil should avoid use.

7. Can Vilitra 60 be taken with food?

Yes, Vilitra 60 can be taken with or without food. However, high-fat meals may slightly delay the absorption of vardenafil.

8. How long does Vilitra 60 stay in the system?

Vardenafil has an active half-life of approximately 5 to 7 hours. The effects of the medication typically last for up to 4 to 5 hours following administration.

9. Does Vilitra 60 cure erectile dysfunction?

No, Vilitra 60 does not cure erectile dysfunction. It is a treatment that helps manage the condition by enabling erections during sexual activity. It does not increase sexual desire.

10. Can Vilitra 60 be combined with other medications?

Vardenafil can interact with alpha-blockers, antihypertensives, certain antifungals, macrolide antibiotics, HIV protease inhibitors, and grapefruit products. Patients should inform their healthcare provider of all medications they are taking before using Vilitra 60.

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References and Reputable Sources

• MedlinePlus – Vardenafil Drug Information: https://medlineplus.gov/druginfo/meds/a603035.html 

• DailyMed – Vardenafil Tablet Labeling: https://dailymed.nlm.nih.gov 

• PubMed – Vardenafil Mechanism of Action: https://pubmed.ncbi.nlm.nih.gov/12027779/ 

• FDA – Vardenafil Prescribing Information: https://www.accessdata.fda.gov 

• Drugs.com – Vardenafil Safety Information: https://www.drugs.com 

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Vilitra 60 offers a reliable and effective option for men seeking to manage erectile dysfunction. With its proven efficacy profile and rapid onset of action, this product from Centurion Laboratories represents a trusted choice for those requiring vardenafil therapy.

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