Description

ZPHC Testolone (RAD-140) – 10 mg Tablets

Product Description

Testolone, scientifically designated as RAD-140, represents a significant advancement in the class of non-steroidal selective androgen receptor modulators (SARMs). ZPHC presents this pharmaceutical-grade compound in a precise 10 mg tablet formulation, providing researchers and investigators with a standardized dosage form for their non-clinical studies .

RAD-140 is a potent, orally bioavailable SARM that demonstrates high affinity for the androgen receptor with a Ki value of 7 nM . This research compound exhibits favorable selectivity over other steroid hormone nuclear receptors, with the closest off-target interaction being the progesterone receptor at an IC50 of 750 nM . The molecular formula is C20H16ClN5O2 with a molecular weight of 393.83 g/mol and a CAS number of 1182367-47-0 .

Preclinical investigations have demonstrated that RAD-140 exhibits good bioavailability in animal models, with oral bioavailability ranging from 27-63% in rats and 65-75% in primates . The compound shows high metabolic stability with a half-life exceeding 2 hours in microsomal preparations across multiple species . In rodent models, RAD-140 administration at doses of 0.03-0.3 mg/kg for 11 days demonstrated increases in levator ani and prostate weights in immature castrated rats, suggesting anabolic activity .

The tissue-selective profile of RAD-140 is of particular research interest. Studies indicate that SARMs like RAD-140 may offer tissue-specific androgen receptor modulation, potentially distinguishing anabolic effects on muscle from androgenic effects on reproductive tissues . This characteristic is attributed to the non-steroidal structure of SARMs, which do not undergo aromatization or 5-alpha-reduction in the same manner as steroidal androgens .

ZPHC maintains rigorous quality control standards, with each batch undergoing laboratory testing to confirm >99% purity. The tablets are film-coated and scored, allowing for precise dose manipulation in research protocols. Each tamper-evident box contains sealed blisters with scratch-code authenticity verification and is shipped with tracked worldwide delivery.

Product Specifications

• Active Ingredient: Testolone (RAD-140)

• Dosage Form: Film-coated, scored tablets

• Strength: 10 mg per tablet

• Quantity: 100 tablets per box

• Purity: >99% by laboratory analysis

• Quality Control: Heavy metal and microbiological clearance

• Packaging: Sealed blisters in tamper-evident box

• Authentication: Scratch-code verification system

Research Applications

Testolone (RAD-140) is indicated for research purposes only. Investigational applications may include:

• Androgen receptor signaling studies

• Tissue-selective androgen receptor modulation research

• Investigation of anabolic pathways in musculoskeletal tissues

• Preclinical evaluation of neuroprotective properties

• Studies of SARMs pharmacology and pharmacokinetics

Cycle Parameters

Typical research protocols utilize dosages ranging from 10 to 30 mg administered daily for cycles of 6 to 8 weeks. The scored tablet design facilitates splitting for 5 mg introductory dosing when required by specific research protocols. Combination studies with other research compounds such as Ligandrol or Ostarine have been documented in the research literature.

Frequently Asked Questions

1. What is the chemical structure and classification of Testolone (RAD-140)?

Testolone (RAD-140), also known as Vosilasarm, is a non-steroidal selective androgen receptor modulator with the chemical name 2-chloro-4-[[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino]-3-methylbenzonitrile. Its molecular formula is C20H16ClN5O2 with a molecular weight of 393.83 g/mol .

2. What is the mechanism of action of RAD-140?

RAD-140 functions as an androgen receptor ligand that binds selectively to androgen receptors in a tissue-specific manner. This binding activates androgenic signaling pathways, potentially differentiating anabolic effects on muscle tissue from androgenic effects on reproductive tissues .

3. What purity standards does ZPHC maintain for this product?

ZPHC maintains rigorous quality control standards with each batch undergoing laboratory testing to confirm >99% purity. Products undergo heavy metal and microbiological clearance testing to ensure research-grade quality.

4. What is the recommended storage protocol?

Powder should be stored at -20°C for long-term storage (up to 3 years) or at 4°C for up to 2 years. Solutions should be stored at -80°C for up to 6 months or -20°C for up to 1 month. The product is stable at room temperature during ordinary shipping .

5. What is the solubility profile of RAD-140?

RAD-140 demonstrates ≥100 mg/mL solubility in DMSO, with minimal solubility in water (<1 mg/mL) and ethanol. Formulation recommendations include 10% DMSO + 40% PEG300 + 5% Tween80 + 45% saline for solution preparation .

6. What biological targets does RAD-140 affect?

RAD-140 primarily targets the androgen receptor with a Ki of 7 nM. It demonstrates good selectivity over other steroid hormone nuclear receptors, with the closest off-target being the progesterone receptor at an IC50 of 750 nM .

7. What research has been conducted on RAD-140?

Preclinical studies have shown RAD-140 exhibits good bioavailability (27-63% in rats, 65-75% in primates) and metabolic stability. It has demonstrated neuroprotective properties in rodent models and tissue-specific androgen action in castrated rat models. A Phase 1 human study has investigated its safety profile at doses of 50-150 mg daily .

8. What safety considerations should be noted?

Phase 1 clinical studies have reported that the most frequent treatment-emergent adverse events included elevated AST (59.1%), ALT (45.5%), and total blood bilirubin (27.3%). The maximum tolerated dose was established at 100 mg daily. Treatment-related adverse events occurred in 77.3% of participants, with 31.8% being Grade 3 events .

9. Is this product suitable for human consumption?

This product is intended for research purposes only and is not approved for human or veterinary use. It is sold exclusively for non-clinical laboratory investigations and scientific studies .

10. How are the tablets packaged and authenticated?

The tablets are supplied in sealed blisters contained within a tamper-evident box. Each unit features a scratch-code authenticity verification system to ensure product integrity and identification.

Ordering Information

Regular Price: $69.00
**Current Offer:** $45.00

Secure tracking is provided for worldwide shipping.

Call to Action

Researchers and investigators are invited to acquire this pharmaceutical-grade Testolone (RAD-140) formulation for their non-clinical studies. The combination of ZPHC quality manufacturing, precise 10 mg dosing, and comprehensive quality control documentation supports rigorous research protocols.

Place your order at: https://anabolicsteroidsonline.shop/