Description

GHK-Cu ZPHC — 50 mg KIT (5 vials × 10 mg)

High-Purity Copper Peptide Complex for Advanced Research Applications

The GHK-Cu ZPHC 50 mg Kit provides researchers with a premium-quality copper tripeptide formulation designed for advanced investigative protocols. This complete kit includes five lyophilised vials containing 10 mg each of GHK-Cu (Copper Tripeptide-1), supplemented with sterile diluent for precise reconstitution.

GHK-Cu is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine, first isolated from human plasma and subsequently identified in saliva and urine . Research has demonstrated that endogenous GHK levels decline significantly with age, prompting scientific investigation into its regenerative properties .

Product Specifications

• Total peptide content: 50 mg (5 vials × 10 mg)

• Purity: ≥ 98.9% verified by HPLC

• Manufacturing standards: GMP and ISO 17034:2016 certified

• Authentication: ZPHC scratch-code verification system

• Form: Lyophilised powder for research use

• Included: Sterile diluent for reconstitution

• Storage: 2-8°C recommended for preserved stability

• Packaging: Cold-chain packed with tamper-evident vials

Research-Backed Applications

Regenerative Tissue Research

GHK-Cu has been extensively studied for its role in tissue repair and regeneration. Research indicates that this copper peptide complex may promote extracellular matrix synthesis and support the production of collagen and decorin . Studies have demonstrated that GHK-Cu can significantly reduce levels of pro-inflammatory cytokines and promote the resolution of inflammation by modulating immune cell activity .

Cellular Renewal and Structural Support

Investigations into the anti-aging activity of GHK-Cu have shown promising results in supporting cellular renewal and maintaining dermal structure. The copper component serves as a cofactor for lysyl oxidase and other collagen cross-linking enzymes, potentially enhancing matrix stability . Research has demonstrated that GHK-Cu may stimulate collagen I and III synthesis and promote glycosaminoglycan deposition .

Hair Follicle Research

Scientific literature suggests GHK-Cu may have implications for hair growth research protocols. The peptide may promote fibroblast proliferation resulting in collagen synthesis, which could support scalp health and blood flow to hair follicles . GHK-Cu has also been shown to suppress the overexpression of transforming growth factor-beta (TGF-β)1 that has been observed in hereditary hair loss research .

Antioxidant and Anti-Inflammatory Properties

Studies have demonstrated that GHK-Cu possesses significant antioxidant and anti-inflammatory effects . Research indicates that GHK-Cu can reduce levels of inflammatory factors including NO, TNF-α, IL-1β, and IL-6 . The peptide has been shown to reduce oxidative stress by decreasing reactive oxygen species levels while enhancing superoxide dismutase activity .

Reconstitution Protocol

For optimal results, adhere to the following reconstitution procedure:

1. Using aseptic technique, add the provided sterile diluent to the lyophilised powder

2. Swirl gently until the powder is fully dissolved

3. Avoid vigorous shaking to prevent degradation of the peptide structure

4. Use immediately or store at 2-8°C for short-term storage

5. Protect from light exposure during storage

Quality Assurance

The GHK-Cu ZPHC product line maintains rigorous quality standards:

• Purity verification: High-performance liquid chromatography (HPLC) confirms ≥98.9% purity

• Manufacturing certification: Produced under Good Manufacturing Practice (GMP) and ISO 17034:2016 standards

• Authentication system: Each kit features a unique scratch-code for verification

• Cold-chain integrity: Shipped in temperature-controlled packaging to preserve product stability

Frequently Asked Questions

1. What is the recommended storage temperature for lyophilised GHK-Cu powder?

Lyophilised GHK-Cu powder should be stored at 2-8°C for short-term preservation. For extended storage, temperatures of -20°C or below are recommended, where the product can remain stable for up to three years . The product remains stable at room temperature for several weeks, however colder temperatures are recommended to preserve integrity over extended periods .

2. How should I store reconstituted GHK-Cu solutions?

Reconstituted GHK-Cu solutions should be stored at 2-8°C and protected from light. When reconstituted with bacteriostatic water, the solution is typically stable for up to 30 days. It is advisable to avoid repeated freeze-thaw cycles as this can degrade the peptide .

3. What is the optimal pH range for maintaining GHK-Cu stability?

GHK-Cu is most stable in a neutral to slightly acidic pH range, ideally between 5.5 and 6.5. Strongly acidic (pH < 4.0) or alkaline (pH > 7.4) conditions can lead to dissociation of the copper ion from the peptide and cause hydrolytic cleavage, thereby reducing biological activity .

4. Can I freeze reconstituted GHK-Cu solutions for extended storage?

Freezing reconstituted GHK-Cu solutions is not generally recommended, as freeze-thaw cycles can degrade the peptide structure. For longer-term storage of reconstituted peptide, it is preferable to aliquot the solution into single-use sterile vials and store them at -20°C to minimise freeze-thaw cycles .

5. What solvent is recommended for reconstituting lyophilised GHK-Cu?

The standard and scientifically recommended solvent for reconstituting lyophilised GHK-Cu is bacteriostatic water, which contains 0.9% benzyl alcohol to inhibit microbial growth. Sterile water for injection can also be used, however the reconstituted solution will have a shorter shelf-life due to the lack of a preservative .

6. Is GHK-Cu sensitive to light and air?

Yes, GHK-Cu is sensitive to both light and air. Exposure to light can trigger breakdown of the peptide chain, and oxygen can oxidise the copper ion, reducing activity. Both lyophilised powder and reconstituted solutions should be stored in dark or amber vials and protected from direct light .

7. What purity level does this GHK-Cu product provide?

The GHK-Cu ZPHC product provides a purity of ≥98.9%, verified by high-performance liquid chromatography (HPLC). This high-purity formulation is produced under GMP and ISO 17034:2016 standards, ensuring quality and consistency for research applications.

8. Does GHK-Cu have antioxidant properties?

Research has demonstrated that GHK-Cu possesses significant antioxidant properties. Studies have shown that GHK-Cu can reduce oxidative stress by decreasing reactive oxygen species levels while enhancing superoxide dismutase activity . The peptide also blocks the formation of reactive oxygen and carbonyl species and detoxifies toxic products of lipid peroxidation .

9. What research applications is GHK-Cu used for?

GHK-Cu is investigated for multiple research applications including wound healing, tissue regeneration, collagen stimulation, dermal structure support, and hair follicle health research . Studies have also explored its potential implications for inflammatory conditions and oxidative stress research .

10. How do I verify the authenticity of this product?

Each GHK-Cu ZPHC kit features a unique scratch-code authentication system. To verify the product’s authenticity, locate the scratch-code on the packaging and authenticate it through the ZPHC official verification system.

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Take the Next Step in Your Research

The GHK-Cu ZPHC 50 mg Kit represents a significant investment in high-quality research materials. With its verified purity, rigorous manufacturing standards, and comprehensive documentation, this product is designed to support meaningful scientific investigation.

Secure your GHK-Cu ZPHC 50 mg Kit today for your research protocols.

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References:

ScienceDirect. (2025). An injectable hydroxyapatite microsphere filler loaded with GHK-Cu tripeptide for anti-Inflammatory and antioxidant. 

Fagron Academy. (2026). GHK-Cu: Beyond Cosmetic Hype. 

BenchChem. (2025). Long-term storage and stability of GHK-Cu stock solutions. 

PlexusDx. (2026). Copper Peptide GHK-Cu: Biomarker Context and Clinical Personalization. 

Chinese Academy of Sciences. GHK-Cu may Prevent Oxidative Stress in Skin by Regulating Copper and Modifying Expression of Numerous Antioxidant Genes.