Description

S4 (ANDARINE) 25mg 90tabs

Andarine S-4 (SARM) – Complete Product Overview

What is Andarine S-4?

Andarine, also known by its developmental codes GTx-007 and S-4, is a first-generation selective androgen receptor modulator (SARM) originally developed by GTX, Inc for the treatment of muscle wasting, osteoporosis, and benign prostatic hyperplasia. As a non-steroidal androgen receptor agonist with a Ki of 4 nM, Andarine exhibits tissue-selective anabolic activity, preferentially targeting muscle and bone tissue.

Andarine functions as a full agonist at androgen receptors in muscle, bone, and the pituitary gland, while demonstrating reduced androgenic activity in other tissues. This selective mechanism is what distinguishes SARMs from traditional anabolic steroids, potentially offering a more targeted approach to muscle development and body composition improvement.

It is important to note that clinical trials for Andarine have been discontinued and the compound is not approved for human use. Research into SARMs for human use remains limited, and the full risk profile—particularly regarding long-term health impacts—has not been established.

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Key Benefits and Applications

Andarine S-4 is recognized within the bodybuilding community for several distinct properties:

Lean Muscle Preservation: During caloric deficits, Andarine helps maintain lean muscle tissue while promoting fat loss, making it a valuable compound for cutting phases.

Fat Reduction: Users report significant reductions in body fat percentage, with some anecdotal accounts indicating losses of 3-5% body fat while preserving muscle mass.

Increased Muscle Hardness and Vascularity: Andarine is known for producing a “dry” appearance, enhancing muscle definition and vascularity.

Bone Density Support: Animal studies have demonstrated Andarine’s potential to increase bone density and muscle mass.

Strength Enhancement: Users commonly report noticeable strength increases within the first two weeks of use.

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Recommended Dosage Protocols

Dosage recommendations vary based on the user’s specific goals:

Cutting Stack

For cutting cycles, the recommended dosage ranges from 25 to 50 mg per day. This dosage is intended to provide enhanced endurance, facilitate fat loss, and support muscle preservation during caloric restriction. Starting at the lower end of this range (25 mg) is advised to assess individual tolerance.

Bulking Stack

For bulking purposes, a dosage of 20 to 25 mg per day is typically recommended over an 8-week cycle to achieve optimal results. This lower dosage range helps mitigate the risk of side effects while still providing anabolic support for muscle growth.

Administration Guidelines

• Split daily doses into smaller administrations to maintain stable blood levels and reduce peak concentrations that may contribute to side effects

• Begin with the lowest effective dose and titrate upward only as tolerance allows

• Cycle duration typically ranges from 6 to 8 weeks

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Common Stacking Combinations

Andarine S-4 is frequently combined with other compounds to enhance specific outcomes:

Bulking Stack: S-4 combined with YK-11 and MK-677, with the optional addition of MK-2866 (Ostarine). This combination is designed to maximize anabolic signaling, growth hormone secretion, and muscle protein synthesis.

Cutting Stack: Andarine is often used solo or in combination with other SARMs to preserve muscle while accelerating fat loss.

Comparison to Traditional Compounds: Andarine is considered comparable to Winstrol (stanozolol) and Anavar (oxandrolone) in terms of its anabolic profile, though with a potentially different side effect profile due to its selective mechanism.

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Potential Side Effects

Users should be aware of the following potential adverse effects associated with Andarine S-4 use:

Visual Disturbances: The most commonly reported side effect involves vision changes, including yellow-tinted vision (xanthopsia), difficulty adapting to darkness, and reduced night vision. These effects typically manifest within 3 to 7 days of use and resolve within 5 to 7 days after discontinuation. Approximately 30-40% of users at moderate doses (50 mg daily) experience these effects.

Testosterone Suppression: Andarine can suppress the hypothalamic-pituitary-testicular axis with prolonged use. This suppression may result in reduced endogenous testosterone production, necessitating post-cycle therapy (PCT) to restore natural hormone levels.

Hepatic Stress: As with many oral compounds, Andarine may place stress on the liver. Users with pre-existing liver conditions should exercise extreme caution.

Cardiovascular Effects: SARMs have been associated with adverse effects on heart health, though the specific cardiovascular impact of Andarine requires further research.

Virilization in Females: Female users may experience virilization effects, including deepening of the voice, hirsutism, and clitoral enlargement.

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Important Safety Information

Andarine is classified as an experimental medicine and is not approved for human consumption by any regulatory authority. The Therapeutic Goods Administration (TGA) warns that SARMs carry unknown health risks due to limited research. Andarine is covered by the Poisons Standard, and access without authority is illegal in many jurisdictions, potentially resulting in fines or imprisonment. The compound is prohibited at all times for athletes under anti-doping regulations.

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Frequently Asked Questions

1. What is Andarine S-4 and how does it work?

Andarine S-4 (GTx-007) is a selective androgen receptor modulator (SARM) that binds to androgen receptors in muscle and bone tissue, acting as a partial agonist to promote anabolic activity while minimizing androgenic effects in other tissues. It was originally developed to treat muscle wasting and osteoporosis.

2. What is the recommended dosage for Andarine S-4?

For cutting cycles, the typical dosage ranges from 25 to 50 mg per day. For bulking, a lower dosage of 20 to 25 mg per day over an 8-week period is commonly recommended. Beginners should start at 25 mg per day to assess tolerance.

3. What are the most common side effects of Andarine S-4?

The most frequently reported side effects include visual disturbances such as yellow-tinted vision, difficulty with night vision, and impaired dark adaptation. Testosterone suppression is also common with prolonged use. Other potential effects include liver stress and cardiovascular impacts.

4. How long does it take to see results with Andarine S-4?

Users typically report noticeable strength increases within 1.5 to 2 weeks of starting use. Visible changes in body composition, including increased muscle hardness and fat loss, generally become apparent within 3 to 4 weeks of consistent use.

5. Is Andarine S-4 legal?

Andarine is not approved for human use and is classified as an experimental medicine. It is covered by the Poisons Standard in many jurisdictions, and access without authority is illegal. It is also prohibited for athletes at all times under anti-doping regulations.

6. Can Andarine S-4 be stacked with other compounds?

Yes, Andarine is commonly stacked with other compounds. A typical bulking stack includes S-4, YK-11, and MK-677, with the optional addition of MK-2866 (Ostarine). For cutting, it is often used solo or with complementary compounds to enhance fat loss while preserving muscle.

7. How does Andarine S-4 compare to traditional anabolic steroids?

Andarine is considered comparable to Winstrol and Anavar in terms of its anabolic effects. However, as a SARM, it is designed to selectively target androgen receptors in muscle and bone, potentially reducing the androgenic side effects associated with traditional steroids.

8. What is the cycle length for Andarine S-4?

Typical cycle lengths range from 6 to 8 weeks. Prolonged use beyond 8 weeks increases the risk of testosterone suppression and other adverse effects. Post-cycle therapy is generally recommended following a cycle to restore natural hormone production.

9. Are the vision side effects from Andarine S-4 permanent?

Current evidence suggests that vision side effects from Andarine are temporary and reversible. Symptoms typically appear within 3 to 7 days of use and resolve within 5 to 7 days after discontinuation. There is no documented evidence of permanent vision damage from Andarine use.

10. Is post-cycle therapy (PCT) necessary after using Andarine S-4?

Yes, PCT is generally recommended following an Andarine cycle due to the compound’s potential to suppress endogenous testosterone production. PCT helps restore natural hormone levels and mitigate the effects of suppression. The specific PCT protocol should be determined based on individual factors and cycle duration.

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Scientific References

• National Center for Advancing Translational Sciences (NCATS) Inxight: Andarine – https://drugs.ncats.io/drug/7UT2HAH49H[reference:47]

• Wikipedia: Andarine – https://en.wikipedia.org/wiki/Andarine[reference:48]

• PubMed: Mass spectrometric characterization of urinary metabolites of andarine (S-4) – https://pubmed.ncbi.nlm.nih.gov/[reference:49]

• Sport Integrity Australia: Don’t risk using Andarine – https://www.sportintegrity.gov.au/news/integrity-blog/2019-12/dont-risk-using-andarine[reference:50]

• SelfDecode: Andarine (S4) Uses, Dangers and Side Effects – https://drugs.selfdecode.com/blog/andarine-s4/[reference:51]

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Andarine S-4 represents a tried-and-true first-generation SARM with a well-established profile among experienced users. Whether your goal is cutting, bulking, or body recomposition, this compound offers targeted anabolic support with a distinct mechanism of action.

To purchase authentic Andarine S-4 and explore our complete range of performance compounds, visit:

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